R & D

Somatic Cell Therapy (Fibroblast)

Cause

Changes in the dermis layer due to aging (the cause of aging)
As aging progresses, the density of collagen in the dermal layer, and the thickness and length of the collagen fibers decrease.

Process

Cure skin is a therapeutic agent that can fundamentally improve damage of the dermal layer. It is a method of culturing and propagating in vitro, the patient’s own fibroblast cells, and then injecting into the patient’s scar and wrinkles. The injected cells migrate and engraft to the dermal damage site and begin to produce key components of the extracellular matrix, including collagen and elastin. Since the production of the extracellular matrix reacts to the control mechanisms of the human body, there is no risk of over production.

Prediction

Changes in collagen production by fibroblast stimulation Fibroblasts respond to physical and chemical stimuli such as cell proliferation and collagen production. This is due to differences in young and aged skin tissue, with high density collagen production in young skin tissue due to sufficient mechanical stimulation, and low density collagen arising in aging skin due to reduced stimulation.

Clinical Tests

-Cureskin Clinical Test (clinical trials stage 1/2)